Product Description

🔹 Product Overview
Doxorex 50 mg Injection contains Doxorubicin Hydrochloride 50 mg, an anthracycline antineoplastic medicine used as part of chemotherapy protocols for various types of cancer. Doxorubicin works primarily by interfering with DNA replication and repair in cancer cells, thereby inhibiting their growth and multiplication.


🔹 Composition
Active Ingredient: Doxorubicin Hydrochloride
Strength: 50 mg
Presentation: 50 mg vial
Dosage Form: Injection / powder for injection
Route: Intravenous administration
Therapeutic Class: Anthracycline antineoplastic / Cytotoxic chemotherapy agent

🔹 Uses And Indications
Doxorex 50 mg may be included in chemotherapy protocols for:
Breast cancer
Lymphomas
Leukemias
Sarcomas
Ovarian cancer
Lung cancer
Other selected solid tumors and hematological malignancies
The specific indication and chemotherapy regimen depend on the type, stage and characteristics of the cancer and the treating oncologist's protocol.

🔹 How It Works
Doxorubicin exerts its anticancer effect through several mechanisms, including DNA intercalation, inhibition of topoisomerase II and generation of free radicals. These actions interfere with DNA replication and repair, ultimately inhibiting cancer-cell growth and promoting cancer-cell death.

🔹 Key Benefits
Provides potent anthracycline-based anticancer activity.
Used in established chemotherapy protocols for a wide range of malignancies.
Can be combined with other anticancer medicines depending on the treatment regimen.
Available as a 50 mg injectable vial.


🔹 Dosage And Administration
Doxorex 50 mg Injection must be administered only by qualified healthcare professionals.
The dose and treatment schedule are individualized according to the cancer type, chemotherapy protocol, body surface area, blood counts, liver function, previous anthracycline exposure and overall clinical condition.
The medicine is administered by the intravenous route following appropriate preparation and dilution according to the approved product instructions. It should not be self-administered.

🔹 Possible Side Effects
Doxorubicin may cause:
Nausea and vomiting
Loss of appetite
Fatigue
Hair loss
Mouth sores or mucositis
Decreased blood-cell counts
Increased risk of infections
Low platelet count
Skin or nail changes
Red discoloration of urine temporarily after administration
Important serious adverse effects can include cardiotoxicity, severe bone-marrow suppression and tissue injury if extravasation occurs.

🔹 Precautions And Warnings
Use only under specialist oncology supervision.
Cardiac function should be assessed before and, when appropriate, during treatment because cumulative doxorubicin exposure can cause cardiomyopathy.
Blood counts should be monitored because doxorubicin can cause significant bone-marrow suppression.
Liver function may require assessment because dose adjustment may be necessary in hepatic impairment.
Inform the doctor about previous treatment with anthracyclines or other potentially cardiotoxic medicines.
Careful administration is required because accidental leakage outside the vein can cause severe local tissue injury.
Inform the healthcare professional about all medicines and cancer treatments being received, including radiotherapy.
Pregnancy should be avoided during treatment because doxorubicin can cause fetal harm.
Breastfeeding should be avoided during treatment unless specifically advised otherwise by the treating physician.

🔹 Storage
Store Doxorex 50 mg Injection according to the manufacturer's labeled storage conditions. Keep the vial protected from excessive heat and light and maintain appropriate pharmaceutical storage conditions. Follow the current product insert for exact storage temperature and handling requirements.