Product Description

🔹 Product Overview
Estrofem 2 mg Tablet contains Estradiol 2 mg (as estradiol hemihydrate), an estrogen hormone replacement medicine used for the treatment of symptoms associated with estrogen deficiency in postmenopausal women. It may also be used for prevention of osteoporosis in selected postmenopausal women at increased risk of fractures.
Estradiol replaces estrogen that the body produces at lower levels after menopause and helps relieve symptoms associated with estrogen deficiency.

🔹 Composition
Active Ingredient: Estradiol hemihydrate
Strength: 2 mg
Presentation: 2 mg tablet
Dosage Form: Film-coated tablet
Route: Oral
Therapeutic Class: Estrogen / Hormone Replacement Therapy (HRT)


🔹 Uses And Indications
Estrofem 2 mg may be used for:
Hormone Replacement Therapy (HRT) for symptoms of estrogen deficiency after menopause
Relief of menopausal symptoms associated with reduced estrogen levels
Prevention of osteoporosis in selected postmenopausal women at increased risk of fractures when other approved treatments are unsuitable
Estrogen replacement in postmenopausal women following natural or surgical menopause
Estrofem is particularly intended as an estrogen-only HRT for women who have undergone hysterectomy and therefore do not require combined estrogen/progestogen therapy.

🔹 How It Works
Estradiol is a form of estrogen that is biologically similar to the body's naturally occurring estrogen. After menopause, reduced estrogen production can contribute to symptoms such as hot flushes and vaginal symptoms and can increase bone loss. Estrofem replaces estrogen and helps restore estrogen activity in the body.

🔹 Key Benefits
Helps relieve symptoms associated with estrogen deficiency after menopause.
Provides estrogen replacement through oral administration.
Helps reduce postmenopausal bone loss in appropriately selected women.
Contains 2 mg estradiol in each film-coated tablet.
Available in a convenient oral tablet formulation.

🔹 Dosage And Administration
Estrofem 2 mg Tablet should be taken only as prescribed by a qualified healthcare professional.
The usual administration is one tablet orally once daily without interruption, but the appropriate dose and duration should be individualized according to the patient's symptoms, medical history and treatment response. The lowest effective dose for the shortest appropriate duration is generally recommended for menopausal symptom treatment.
Women who have an intact uterus generally require an appropriate progestogen in addition to estrogen therapy to reduce the risk of endometrial hyperplasia and cancer.

🔹 Possible Side Effects
Estrofem may cause:
Headache
Breast tenderness or breast pain
Nausea
Abdominal discomfort
Fluid retention
Changes in mood
Vaginal bleeding or spotting
Changes in body weight
Skin reactions
Hormone replacement therapy may also be associated with more serious risks, including venous thromboembolism, stroke and certain hormone-dependent cancers, depending on individual factors and duration of treatment.

🔹 Precautions And Warnings
Use only under appropriate medical supervision.
Estrofem should not be used in patients with certain estrogen-dependent cancers, unexplained vaginal bleeding, previous or current venous thromboembolism, active liver disease or other contraindications specified in the prescribing information.
Inform the doctor about any history of blood clots, stroke, heart disease, liver disease or breast cancer.
Report unexplained vaginal bleeding promptly.
Regular breast examinations and appropriate screening should be maintained according to medical advice.
Estrogen therapy may increase the risk of blood clots; seek urgent medical attention for sudden chest pain, breathlessness or painful swelling of a leg.
Patients with an intact uterus should discuss the need for concomitant progestogen therapy with their doctor.
Inform the doctor about all medicines and supplements being taken because some medicines can affect estrogen metabolism.
Estrofem contains lactose, which should be considered in patients with certain lactose-intolerance disorders.

🔹 Storage
Store Estrofem 2 mg Tablets according to the manufacturer's labeled storage conditions. Keep the tablets in their original packaging, protected from excessive heat and moisture, and out of reach of children. Follow the current product package insert for the exact storage temperature.