๐น Product Overview
IMATIB 400 mg Tablet is a targeted anticancer medicine used for the treatment of certain types of cancers, especially blood cancers and gastrointestinal stromal tumors (GIST). It contains Imatinib Mesylate 400 mg, a Tyrosine Kinase Inhibitor (TKI) that works by blocking specific abnormal proteins responsible for uncontrolled cancer cell growth.
๐น Key Uses
Treatment of Chronic Myeloid Leukemia (CML)
Treatment of certain cases of Acute Lymphoblastic Leukemia (ALL) with specific genetic markers
Management of Gastrointestinal Stromal Tumors (GIST)
Treatment of Dermatofibrosarcoma Protuberans (DFSP)
Management of certain rare bone marrow disorders such as aggressive systemic mastocytosis when indicated
Helps control abnormal cancer cell growth and disease progression
๐น Composition
Active Ingredient: Imatinib Mesylate 400 mg
Drug Class: Tyrosine Kinase Inhibitor (TKI) / Targeted Cancer Therapy
Dosage Form: Oral Tablet
๐น How It Works
IMATIB 400 mg contains Imatinib, which blocks specific enzymes called tyrosine kinases. These enzymes send signals that promote abnormal cancer cell growth multiplication. By inhibiting these signals, Imatinib helps slow down the growth and spread of cancer cells, particularly in cancers driven by abnormal kinase activity such as BCR-ABL positive leukemia.
๐น Key Benefits
Targeted therapy for specific cancer conditions
Helps control growth of abnormal blood cells
Reduces activity of cancer-causing signaling pathways
Oral treatment option for long-term cancer management
Helps improve disease control when used according to an oncologistโs treatment plan
๐น Dosage and Administration
Take only as prescribed by an oncologist or specialist.
Usually taken with food and a full glass of water to reduce stomach irritation.
Swallow the tablet whole; do not crush or chew unless advised by a healthcare professional.
Take at the same time each day for consistent drug levels.
Treatment duration depends on cancer type, response, and medical evaluation.
Regular monitoring of blood counts and liver function may be required during therapy.
๐น Possible Side Effects
Common side effects may include:
Swelling (edema), especially around the eyes or ankles
Nausea and vomiting
Diarrhea
Muscle cramps
Joint or bone pain
Skin rash
Fatigue
Abdominal discomfort
Headache
Serious side effects may include:
Severe liver problems
Significant reduction in blood cell counts
Severe fluid retention
Unusual bleeding or infection symptoms
Seek medical advice promptly if severe or persistent symptoms occur.
๐น Precautions
Use only under the supervision of an oncology specialist.
Inform your doctor about liver disease, kidney problems, heart conditions, or previous chemotherapy.
Regular blood tests may be required to monitor treatment safety.
Inform your doctor about all medicines, supplements, and herbal products you are taking.
Avoid pregnancy during treatment unless specifically discussed with your healthcare provider.
Do not stop IMATIB suddenly without medical advice, even if symptoms improve.
Important: Always follow your healthcare provider's instructions when using this medication.
Note: This is general guidance. For specific instructions, please consult your healthcare provider or refer to the package insert.
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